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Richard Berger Selected Research

Adrenergic Agonists (Adrenergic Receptor Agonist)

1/2017Investigation of piperazine benzamides as human β3 adrenergic receptor agonists for the treatment of overactive bladder.
1/2016Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder.
2/2014Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder.

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Richard Berger Research Topics

Disease

10Premature Birth (Birth, Premature)
03/2022 - 08/2019
5Hypoxia (Hypoxemia)
03/2013 - 05/2003
4Infections
02/2014 - 12/2003
3Rupture
12/2019 - 05/2014
3Overactive Urinary Bladder (Overactive Bladder)
01/2017 - 02/2014
3Pelvic Pain
12/2008 - 02/2003
2Pain (Aches)
01/2022 - 02/2003
2Ischemia
03/2013 - 09/2008
2Acne Vulgaris
08/2007 - 06/2007
2Hypothermia
09/2003 - 11/2002
2Brain Ischemia (Cerebral Ischemia)
11/2002 - 04/2002
1Acidosis
07/2022
1Pre-Eclampsia (Preeclampsia)
03/2021
1Fever (Fevers)
01/2021
1Tachycardia (Tachyarrhythmias)
01/2021
1Thromboembolism
12/2019
1Prostatitis
12/2008
1Obesity
09/2008
1Erythema
06/2007
1Pruritus (Itching)
06/2007
1Endotoxemia
02/2006
1Brain Injuries (Brain Injury)
01/2006
1Inflammation (Inflammations)
01/2006
1Oligospermia (Oligozoospermia)
01/2005
1Azoospermia
01/2005
1Acute-Phase Reaction
06/2004
1Protein-Energy Malnutrition (Marasmus)
06/2004
1Malnutrition (Nutritional Deficiencies)
06/2004
1Chronic Pain
02/2003
1Body Weight (Weight, Body)
04/2002

Drug/Important Bio-Agent (IBA)

3Adrenergic Agonists (Adrenergic Receptor Agonist)IBA
01/2017 - 02/2014
3CytokinesIBA
09/2008 - 12/2003
3EndotoxinsIBA
02/2006 - 01/2005
2Adrenal Cortex Hormones (Corticosteroids)IBA
03/2022 - 01/2021
2ProgesteroneFDA LinkGeneric
01/2021 - 12/2019
2PiperazineIBA
01/2017 - 09/2008
2Anti-Bacterial Agents (Antibiotics)IBA
02/2014 - 01/2006
2Tretinoin (Retinoic Acid)FDA LinkGeneric
08/2007 - 06/2007
2Nitric Oxide (Nitrogen Monoxide)FDA Link
02/2006 - 01/2005
2SolventsIBA
01/2004 - 04/2002
2FlunarizineIBA
09/2003 - 11/2002
2MagnesiumIBA
09/2003 - 11/2002
2CalciumIBA
09/2003 - 11/2002
1BuffersIBA
07/2022
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
03/2021
1hexanoic acid (hexanoate)IBA
01/2021
117-alpha-Hydroxyprogesterone (17 Hydroxyprogesterone)IBA
01/2021
1E 25 (E-25)IBA
12/2019
1NicotineFDA Link
12/2019
1AmidesIBA
01/2017
1benzamideIBA
01/2017
1BenzamidesIBA
01/2017
1N- (4- ((5- (hydroxy(phenyl)methyl)pyrrolidin- 2- yl)methyl)phenyl)- 4- oxo- 4,6,7,8- tetrahydropyrrolo(1,2- a)pyrimidine- 6- carboxamideIBA
01/2016
1Biomarkers (Surrogate Marker)IBA
05/2014
1AcetanilidesIBA
02/2014
1Polyethylene (Polythene)IBA
02/2014
1Oxygen (Dioxygen)IBA
03/2013
1alfuzosin (UroXatral)FDA Link
12/2008
1alpha Adrenergic ReceptorsIBA
12/2008
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2008
1Interferon-gamma (Interferon, gamma)IBA
09/2008
1imidazoleIBA
09/2008
1RetinoidsIBA
06/2007
1Endothelins (Endothelin)IBA
02/2006
1LipopolysaccharidesIBA
02/2006
1Proteins (Proteins, Gene)FDA Link
01/2006
1acylineIBA
01/2005
1Dutasteride (Avodart)FDA Link
01/2005
1Interleukin-6 (Interleukin 6)IBA
06/2004
1Acute-Phase Proteins (Acute-Phase Protein)IBA
06/2004
1Leucine (L-Leucine)FDA Link
06/2004
1CreatineIBA
01/2004
1Aspartic Acid (Aspartate)FDA Link
11/2002
1Glutamic Acid (Glutamate)FDA Link
11/2002
1Excitatory Amino AcidsIBA
11/2002
1Neuroprotective AgentsIBA
04/2002
1lubeluzoleIBA
04/2002

Therapy/Procedure

7Therapeutics
12/2019 - 11/2002
3Microspheres (Microsphere)
08/2007 - 04/2002
2Pessaries
01/2022 - 11/2019
2Ambulatory Care (Outpatient Care)
12/2019 - 02/2003
2Tertiary Prevention
12/2019 - 08/2019
2Secondary Prevention
10/2019 - 08/2019
2Ligation
03/2013 - 05/2003
1Umbilical Cord Clamping
07/2022
1Prostheses and Implants (Prosthesis)
01/2022
1Bed Rest (Bedrest)
12/2019
1Prenatal Care (Care, Prenatal)
12/2019
1Debridement
02/2014
1Pain Management
01/2006